Going beyond medication side-effects, this session will explore the potential effects of highly effective modulators on clinical practice, clinical trials, and new therapeutics development. A panel of adults with CF and two clinical CF researchers will explore the timeline of expanded Trikafta approval within the U.S. and abroad, and the theoretical impact that highly effective modulators could have on future clinical trials, clinical practice, and even the ability to fundraise. Join this interactive panel session as we explore the possible impacts and gather audience ideas. If you are also interested in learning about current modulator impact on daily life and treatment, make sure to sign up for “Changing CF Care in the Era of Trikafta: Are We There Yet?” in the next round. If you are interested in learning about the genetic-based specific therapies that are in development, sign up for “Beyond Modulators: Genetic Therapies on the Horizon.”